![1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine structure](/static/products/2174/217454-97-2.webp)
1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine
TL;DR: 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine (CAS 217454-97-2) is a chemical compound with molecular formula C16H15ClF3N3O2S and molecular weight 405.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-chloro-5-(trifluoromethyl)phenyl]sulfonyl-4-pyridin-2-ylpiperazine
Also Known As: J1.042.468B, 1-[2-CHLORO-5-(TRIFLUOROMETHYL)BENZENESULFONYL]-4-(PYRIDIN-2-YL)PIPERAZINE, 1-[[2-Chloro-5-(trifluoromethyl)phenyl]sulfonyl]-4-(2-pyridinyl)piperazine, 1-[2-chloro-5-(trifluoromethyl)phenyl]sulfonyl-4-pyridin-2-yl-piperazine, 1-[2-chloro-5-(trifluoromethyl)phenyl]sulfonyl-4-pyridin-2-ylpiperazine
| Molecular Formula | C16H15ClF3N3O2S |
|---|---|
| Molecular Weight | 405.05 g/mol |
| LogP | 3.2647 |
| Topological Polar Surface Area | 53.51 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 405.05255 |
| Heavy Atoms | 26 |
| Complexity | 883.35815 |
Chemical Identifiers
| CAS Number | 217454-97-2 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=N2)S(=O)(=O)C3=C(C=CC(=C3)C(F)(F)F)Cl |
Product Overview
1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine (CAS 217454-97-2), with molecular formula C16H15ClF3N3O2S and molecular weight 405.05 g/mol. IUPAC: 1-[2-chloro-5-(trifluoromethyl)phenyl]sulfonyl-4-pyridin-2-ylpiperazine.
Chemical Property Profile of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine
Property Insights of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine
The XLogP value of 3.2647 indicates that 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.51 Ų, 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine?
The CAS number of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine is 217454-97-2.
What is the molecular formula of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine?
The molecular formula of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine is C16H15ClF3N3O2S.
What is the molecular weight of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine?
The molecular weight of 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine is 405.05 g/mol.
Where can I buy 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine?
You can request a quote for 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-[2-Chloro-5-(trifluoromethyl)benzenesulfonyl]-4-(pyridin-2-YL)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.