氟达拉滨
TL;DR: 氟达拉滨 (CAS 21679-14-1) is a chemical compound with molecular formula C10H12FN5O4 and molecular weight 285.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氟达拉滨
2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Also Known As: Fludarabine, 2-Fluoroadenosine, Fludarabine Base, naratriptan, 2'-fluoroadenosine
| Molecular Formula | C10H12FN5O4 |
|---|---|
| Molecular Weight | 285.09 g/mol |
| LogP | -0.6 |
| Topological Polar Surface Area | 140.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.08734 |
| Heavy Atoms | 20 |
| Complexity | 367.0 |
Chemical Identifiers
| CAS Number | 21679-14-1 |
|---|---|
| SMILES | C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N |
| InChIKey | HBUBKKRHXORPQB-UHFFFAOYSA-N |
Product Overview
氟达拉滨 (CAS 21679-14-1), with molecular formula C10H12FN5O4 and molecular weight 285.09 g/mol. IUPAC: 2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol.
Chemical Property Profile of 氟达拉滨
Property Insights of 氟达拉滨
The XLogP value of -0.6 indicates that 氟达拉滨 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.0 Ų indicates high polarity, suggesting 氟达拉滨 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Fludarabine Base has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fludarabine Base?
The CAS number of Fludarabine Base is 21679-14-1.
What is the molecular formula of Fludarabine Base?
The molecular formula of Fludarabine Base is C10H12FN5O4.
What is the molecular weight of Fludarabine Base?
The molecular weight of Fludarabine Base is 285.09 g/mol.
Where can I buy Fludarabine Base?
You can request a quote for Fludarabine Base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fludarabine Base?
Yes, KEHONG BIO provides custom synthesis services for Fludarabine Base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.