JANEX-1
TL;DR: JANEX-1 (CAS 202475-60-3) is a chemical compound with molecular formula C16H15N3O3 and molecular weight 297.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
JANEX-1
4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Also Known As: WHI-P131, Janex 1, jak3 inhibitor i, WHI P131, 4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
| Molecular Formula | C16H15N3O3 |
|---|---|
| Molecular Weight | 297.11 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 76.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 297.11133 |
| Heavy Atoms | 22 |
| Complexity | 350.0 |
Chemical Identifiers
| CAS Number | 202475-60-3 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC |
| InChIKey | HOZUXBLMYUPGPZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
JANEX-1 (CAS 202475-60-3), with molecular formula C16H15N3O3 and molecular weight 297.11 g/mol. IUPAC: 4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol.
Chemical Property Profile of JANEX-1
Property Insights of JANEX-1
The XLogP value of 3.0 indicates that Whi-p131 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.5 Ų falls within the moderate polarity range, balancing permeability and solubility for JANEX-1. Following Lipinski's Rule of Five, Whi-p131 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Whi-p131?
The CAS number of Whi-p131 is 202475-60-3.
What is the molecular formula of Whi-p131?
The molecular formula of Whi-p131 is C16H15N3O3.
What is the molecular weight of Whi-p131?
The molecular weight of Whi-p131 is 297.11 g/mol.
Where can I buy Whi-p131?
You can request a quote for Whi-p131 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Whi-p131?
Yes, KEHONG BIO provides custom synthesis services for Whi-p131 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.