洛沙平
TL;DR: 洛沙平 (CAS 1977-10-2) is a chemical compound with molecular formula C18H18ClN3O and molecular weight 327.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
洛沙平
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
Also Known As: loxapine, Cloxazepine, Oxilapine, Loxapin, Loxitane
| Molecular Formula | C18H18ClN3O |
|---|---|
| Molecular Weight | 327.11 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 28.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 327.11383 |
| Heavy Atoms | 23 |
| Complexity | 450.0 |
| Melting Point | 109-111 °C |
| Solubility | 1.03e-01 g/L |
Chemical Identifiers
| CAS Number | 1977-10-2 |
|---|---|
| SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl |
| InChIKey | XJGVXQDUIWGIRW-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 15 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
洛沙平 (CAS 1977-10-2), with molecular formula C18H18ClN3O and molecular weight 327.11 g/mol. IUPAC: 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine.
Chemical Property Profile of 洛沙平
Property Insights of 洛沙平
The XLogP value of 3.1 indicates that 洛沙平 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.1 Ų, 洛沙平 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 洛沙平 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛沙平?
The CAS number of 洛沙平 is 1977-10-2.
What is the molecular formula of 洛沙平?
The molecular formula of 洛沙平 is C18H18ClN3O.
What is the molecular weight of 洛沙平?
The molecular weight of 洛沙平 is 327.11 g/mol.
Where can I buy 洛沙平?
You can request a quote for 洛沙平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛沙平?
Yes, KEHONG BIO provides custom synthesis services for 洛沙平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.