洛匹那韦
TL;DR: 洛匹那韦 (CAS 192725-17-0) is a chemical compound with molecular formula C37H48N4O5 and molecular weight 628.36 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
洛匹那韦
N-[5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
Also Known As: Lopinavir, Aluvia, Lopinavir-d8, (2R,4S,5S)-Lopinavir, Lopinavir [USAN:INN:BAN]
| Molecular Formula | C37H48N4O5 |
|---|---|
| Molecular Weight | 628.36 g/mol |
| LogP | 5.9 |
| Topological Polar Surface Area | 120.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 15 |
| Exact Mass | 628.3625 |
| Heavy Atoms | 46 |
| Complexity | 940.0 |
Chemical Identifiers
| CAS Number | 192725-17-0 |
|---|---|
| SMILES | CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O |
| InChIKey | KJHKTHWMRKYKJE-UHFFFAOYSA-N |
Product Overview
洛匹那韦 (CAS 192725-17-0), with molecular formula C37H48N4O5 and molecular weight 628.36 g/mol. IUPAC: N-[5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide.
Chemical Property Profile of 洛匹那韦
Property Insights of 洛匹那韦
The XLogP value of 5.9 indicates that 洛匹那韋 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 120.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 洛匹那韦. Following Lipinski's Rule of Five, 洛匹那韋 has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛匹那韋?
The CAS number of 洛匹那韋 is 192725-17-0.
What is the molecular formula of 洛匹那韋?
The molecular formula of 洛匹那韋 is C37H48N4O5.
What is the molecular weight of 洛匹那韋?
The molecular weight of 洛匹那韋 is 628.36 g/mol.
Where can I buy 洛匹那韋?
You can request a quote for 洛匹那韋 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛匹那韋?
Yes, KEHONG BIO provides custom synthesis services for 洛匹那韋 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.