![5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide structure](/static/products/1864/186430-23-9.webp)
5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide
TL;DR: 5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide (CAS 186430-23-9) is a chemical compound with molecular formula C23H23ClFN3O3 and molecular weight 443.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide
5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide
Also Known As: J1.821.339G, 5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide, CHI, N-[1-(4-Fluorobenzyl)-2-(4-hydroxypiperidine-1-yl)-2-oxoethyl]-5-chloro-1H-indole-2-carboxamide
| Molecular Formula | C23H23ClFN3O3 |
|---|---|
| Molecular Weight | 443.14 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 85.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 443.1412 |
| Heavy Atoms | 31 |
| Complexity | 638.0 |
Chemical Identifiers
| CAS Number | 186430-23-9 |
|---|---|
| SMILES | C1CN(CCC1O)C(=O)C(CC2=CC=C(C=C2)F)NC(=O)C3=CC4=C(N3)C=CC(=C4)Cl |
| InChIKey | YDCGVASFVACWKF-UHFFFAOYSA-N |
Product Overview
5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide (CAS 186430-23-9), with molecular formula C23H23ClFN3O3 and molecular weight 443.14 g/mol. IUPAC: 5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide.
Chemical Property Profile of 5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide
Property Insights of 5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide
The XLogP value of 3.8 indicates that J1.821.339G is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide. Following Lipinski's Rule of Five, J1.821.339G has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of J1.821.339G?
The CAS number of J1.821.339G is 186430-23-9.
What is the molecular formula of J1.821.339G?
The molecular formula of J1.821.339G is C23H23ClFN3O3.
What is the molecular weight of J1.821.339G?
The molecular weight of J1.821.339G is 443.14 g/mol.
Where can I buy J1.821.339G?
You can request a quote for J1.821.339G directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for J1.821.339G?
Yes, KEHONG BIO provides custom synthesis services for J1.821.339G and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.