AM251
TL;DR: AM251 (CAS 183232-66-8) is a chemical compound with molecular formula C22H21Cl2IN4O and molecular weight 554.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
AM251
1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
Also Known As: AM251, AM 251, (S)-6-Hydroxy Nicotine, nchembio.86-comp7, AM 251 (pharmaceutical)
| Molecular Formula | C22H21Cl2IN4O |
|---|---|
| Molecular Weight | 554.01 g/mol |
| LogP | 6.5 |
| Topological Polar Surface Area | 50.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 554.01373 |
| Heavy Atoms | 30 |
| Complexity | 585.0 |
Chemical Identifiers
| CAS Number | 183232-66-8 |
|---|---|
| SMILES | CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)I |
| InChIKey | BUZAJRPLUGXRAB-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
AM251 (CAS 183232-66-8), with molecular formula C22H21Cl2IN4O and molecular weight 554.01 g/mol. IUPAC: 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide.
Chemical Property Profile of AM251
Property Insights of AM251
The XLogP value of 6.5 indicates that AM251 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.2 Ų, AM251 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AM251 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AM251?
The CAS number of AM251 is 183232-66-8.
What is the molecular formula of AM251?
The molecular formula of AM251 is C22H21Cl2IN4O.
What is the molecular weight of AM251?
The molecular weight of AM251 is 554.01 g/mol.
Where can I buy AM251?
You can request a quote for AM251 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AM251?
Yes, KEHONG BIO provides custom synthesis services for AM251 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.