SB 228357
TL;DR: SB 228357 (CAS 181629-93-6) is a chemical compound with molecular formula C22H17F4N3O2 and molecular weight 431.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Also Known As: Lopac-S-2318, J1.060.588A, N-(3-Fluoro-5-(pyridin-3-yl)phenyl)-5-methoxy-6-(trifluoromethyl)indoline-1-carboxamide, SID:134222385, N-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
| Molecular Formula | C22H17F4N3O2 |
|---|---|
| Molecular Weight | 431.13 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 54.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 431.1257 |
| Heavy Atoms | 31 |
| Complexity | 634.0 |
Chemical Identifiers
| CAS Number | 181629-93-6 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC(=CC(=C3)C4=CN=CC=C4)F)C(F)(F)F |
| InChIKey | RRJLJKRFFRZRAF-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
SB 228357 (CAS 181629-93-6), with molecular formula C22H17F4N3O2 and molecular weight 431.13 g/mol. IUPAC: N-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide.
Chemical Property Profile of SB 228357
Property Insights of SB 228357
The XLogP value of 4.2 indicates that SB 228357 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.5 Ų, SB 228357 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, SB 228357 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of SB 228357?
The CAS number of SB 228357 is 181629-93-6.
What is the molecular formula of SB 228357?
The molecular formula of SB 228357 is C22H17F4N3O2.
What is the molecular weight of SB 228357?
The molecular weight of SB 228357 is 431.13 g/mol.
Where can I buy SB 228357?
You can request a quote for SB 228357 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for SB 228357?
Yes, KEHONG BIO provides custom synthesis services for SB 228357 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.