PAPP
TL;DR: PAPP (CAS 1814-64-8) is a chemical compound with molecular formula C19H22F3N3 and molecular weight 349.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]aniline
Also Known As: PAPP, p-NH2-PE-Tfmpp, LY 165163, Lopac-S-009, Biomol-NT_000160
| Molecular Formula | C19H22F3N3 |
|---|---|
| Molecular Weight | 349.18 g/mol |
| LogP | 4.0 |
| Topological Polar Surface Area | 32.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 349.17657 |
| Heavy Atoms | 25 |
| Complexity | 399.0 |
| Solubility | >52.4 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 1814-64-8 |
|---|---|
| SMILES | C1CN(CCN1CCC2=CC=C(C=C2)N)C3=CC=CC(=C3)C(F)(F)F |
| InChIKey | GAAKALASJNGQKD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
PAPP (CAS 1814-64-8), with molecular formula C19H22F3N3 and molecular weight 349.18 g/mol. IUPAC: 4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]aniline.
Chemical Property Profile of PAPP
Property Insights of PAPP
The XLogP value of 4.0 indicates that PAPP is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.5 Ų, PAPP exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, PAPP has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of PAPP?
The CAS number of PAPP is 1814-64-8.
What is the molecular formula of PAPP?
The molecular formula of PAPP is C19H22F3N3.
What is the molecular weight of PAPP?
The molecular weight of PAPP is 349.18 g/mol.
Where can I buy PAPP?
You can request a quote for PAPP directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for PAPP?
Yes, KEHONG BIO provides custom synthesis services for PAPP and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.