美托拉宗
TL;DR: 美托拉宗 (CAS 17560-51-9) is a chemical compound with molecular formula C16H16ClN3O3S and molecular weight 365.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
美托拉宗
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
Also Known As: metolazone, Zaroxolyn, Diulo, Mykrox, Oldren
| Molecular Formula | C16H16ClN3O3S |
|---|---|
| Molecular Weight | 365.06 g/mol |
| LogP | 4.1 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 365.0601 |
| Heavy Atoms | 24 |
| Complexity | 594.0 |
| Melting Point | 256 |
| Solubility | 60.3 |
Chemical Identifiers
| CAS Number | 17560-51-9 |
|---|---|
| SMILES | CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl |
| InChIKey | AQCHWTWZEMGIFD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
美托拉宗 (CAS 17560-51-9), with molecular formula C16H16ClN3O3S and molecular weight 365.06 g/mol. IUPAC: 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide.
Chemical Property Profile of 美托拉宗
Property Insights of 美托拉宗
The XLogP value of 4.1 indicates that 美托拉宗 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 美托拉宗. Following Lipinski's Rule of Five, 美托拉宗 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 美托拉宗?
The CAS number of 美托拉宗 is 17560-51-9.
What is the molecular formula of 美托拉宗?
The molecular formula of 美托拉宗 is C16H16ClN3O3S.
What is the molecular weight of 美托拉宗?
The molecular weight of 美托拉宗 is 365.06 g/mol.
Where can I buy 美托拉宗?
You can request a quote for 美托拉宗 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 美托拉宗?
Yes, KEHONG BIO provides custom synthesis services for 美托拉宗 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.