7-Ethyl-10,11-methylenedioxy-20-S-camptothecin
TL;DR: 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin (CAS 169900-78-1) is a chemical compound with molecular formula C23H20N2O6 and molecular weight 420.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5S)-5,14-diethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione
Also Known As: 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin, 7-Ethyl-10,11-methylenedioxycamptothecin, 7-Ethyl-10,11-methylenedioxy-20(S)-camptothecin, 10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7,14-diethyl-7-hydroxy-, (7S)-, (5S)-5,14-diethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione
| Molecular Formula | C23H20N2O6 |
|---|---|
| Molecular Weight | 420.13 g/mol |
| LogP | 1.6 |
| Topological Polar Surface Area | 98.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 420.13214 |
| Heavy Atoms | 31 |
| Complexity | 898.0 |
Chemical Identifiers
| CAS Number | 169900-78-1 |
|---|---|
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=CC6=C(C=C51)OCO6 |
| InChIKey | VPGWXOVUCCDEPV-QHCPKHFHSA-N |
Product Overview
7-Ethyl-10,11-methylenedioxy-20-S-camptothecin (CAS 169900-78-1), with molecular formula C23H20N2O6 and molecular weight 420.13 g/mol. IUPAC: (5S)-5,14-diethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione.
Chemical Property Profile of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin
Property Insights of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin. The TPSA of 98.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin. Following Lipinski's Rule of Five, 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin?
The CAS number of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin is 169900-78-1.
What is the molecular formula of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin?
The molecular formula of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin is C23H20N2O6.
What is the molecular weight of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin?
The molecular weight of 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin is 420.13 g/mol.
Where can I buy 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin?
You can request a quote for 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin?
Yes, KEHONG BIO provides custom synthesis services for 7-Ethyl-10,11-methylenedioxy-20-S-camptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.