Sunitinib
TL;DR: Sunitinib (CAS 1691223-83-2) is a chemical compound with molecular formula C22H27FN4O2 and molecular weight 398.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Also Known As: Sunitinib, Sunitinib-d4, Sunitinib malate, Sunitinib Impurity 31, N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
| Molecular Formula | C22H27FN4O2 |
|---|---|
| Molecular Weight | 398.21 g/mol |
| LogP | 3.33494 |
| Topological Polar Surface Area | 77.23 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 398.2118 |
| Heavy Atoms | 29 |
| Complexity | 973.4321 |
Chemical Identifiers
| CAS Number | 1691223-83-2 |
|---|---|
| SMILES | CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C |
Product Overview
Sunitinib (CAS 1691223-83-2), with molecular formula C22H27FN4O2 and molecular weight 398.21 g/mol. IUPAC: N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide.
Chemical Property Profile of Sunitinib
Property Insights of Sunitinib
The XLogP value of 3.33494 indicates that Sunitinib is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.23 Ų falls within the moderate polarity range, balancing permeability and solubility for Sunitinib. Following Lipinski's Rule of Five, Sunitinib has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sunitinib?
The CAS number of Sunitinib is 1691223-83-2.
What is the molecular formula of Sunitinib?
The molecular formula of Sunitinib is C22H27FN4O2.
What is the molecular weight of Sunitinib?
The molecular weight of Sunitinib is 398.21 g/mol.
Where can I buy Sunitinib?
You can request a quote for Sunitinib directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sunitinib?
Yes, KEHONG BIO provides custom synthesis services for Sunitinib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.