依折麦布
TL;DR: 依折麦布 (CAS 163222-33-1) is a chemical compound with molecular formula C24H21F2NO3 and molecular weight 409.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
依折麦布
(3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Also Known As: Ezetimibe, Spectrum2_000489, Spectrum3_001005, Spectrum4_001133, Spectrum5_001552
| Molecular Formula | C24H21F2NO3 |
|---|---|
| Molecular Weight | 409.15 g/mol |
| LogP | 4.8883 |
| Topological Polar Surface Area | 60.77 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 409.14896 |
| Heavy Atoms | 30 |
| Complexity | 1019.82654 |
Chemical Identifiers
| CAS Number | 163222-33-1 |
|---|---|
| SMILES | C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O |
Product Overview
依折麦布 (CAS 163222-33-1), with molecular formula C24H21F2NO3 and molecular weight 409.15 g/mol. IUPAC: (3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one.
Chemical Property Profile of 依折麦布
Property Insights of 依折麦布
The XLogP value of 4.8883 indicates that 依折麦布 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.77 Ų falls within the moderate polarity range, balancing permeability and solubility for 依折麦布. Following Lipinski's Rule of Five, 依折麦布 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 依折麦布?
The CAS number of 依折麦布 is 163222-33-1.
What is the molecular formula of 依折麦布?
The molecular formula of 依折麦布 is C24H21F2NO3.
What is the molecular weight of 依折麦布?
The molecular weight of 依折麦布 is 409.15 g/mol.
Where can I buy 依折麦布?
You can request a quote for 依折麦布 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 依折麦布?
Yes, KEHONG BIO provides custom synthesis services for 依折麦布 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.