N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide
TL;DR: N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide (CAS 162401-29-8) is a chemical compound with molecular formula C14H10Cl2F2N2O3 and molecular weight 362.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-3-methoxybenzamide
Also Known As: Roflumilast Impurity 54, N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide, BenzaMide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoroMethoxy)-3-Methoxy-, N-(3,5-dichloropyridin-4-yl)-4-difluoromethoxy-3-methoxybenzamide, 3-Methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
| Molecular Formula | C14H10Cl2F2N2O3 |
|---|---|
| Molecular Weight | 362.00 g/mol |
| LogP | 4.2507 |
| Topological Polar Surface Area | 60.45 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 362.00366 |
| Heavy Atoms | 23 |
| Complexity | 708.9137 |
Chemical Identifiers
| CAS Number | 162401-29-8 |
|---|---|
| SMILES | COC1=C(C=CC(=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC(F)F |
Product Overview
N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide (CAS 162401-29-8), with molecular formula C14H10Cl2F2N2O3 and molecular weight 362.00 g/mol. IUPAC: N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-3-methoxybenzamide.
Chemical Property Profile of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide
Property Insights of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide
The XLogP value of 4.2507 indicates that N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.45 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide. Following Lipinski's Rule of Five, N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide?
The CAS number of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide is 162401-29-8.
What is the molecular formula of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide?
The molecular formula of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide is C14H10Cl2F2N2O3.
What is the molecular weight of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide?
The molecular weight of N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide is 362.00 g/mol.
Where can I buy N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide?
You can request a quote for N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.