1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid structure

1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid

TL;DR: 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid (CAS 161806-28-6) is a chemical compound with molecular formula C23H18N4O3S and molecular weight 430.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[2-(1H-indol-3-yl)acetyl]-3-[(E)-[(E)-3-phenylprop-2-enylidene]amino]-2-sulfanylidene-1,3-diazinane-4,6-dione

Also Known As: Barbituric acid, 1-(cinnamylideneamino)-3-(3-indolylacetyl)-2-thio-, 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid, 4,6(1H,3H)-Pyrimidinedione, dihydro-1-(1H-indol-3-ylacetyl)-3-((3-phenyl-2-propenylidene)amino)-2-thioxo-, 1-[(3-Phenyl-2-propenylidene)amino]-2-thioxo-3-[(1H-indol-3-yl)acetyl]-2,3-dihydropyrimidine-4,6(1H,5H)-dione, 1-[2-(1H-indol-3-yl)acetyl]-3-[(3-phenylprop-2-en-1-ylidene)amino]-2-sulfanylidene-1,3-diazinane-4,6-dione

CAS: 161806-28-6
Molecular Formula C23H18N4O3S
Molecular Weight 430.11 g/mol
LogP 3.282
Topological Polar Surface Area 85.84 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 430.10995
Heavy Atoms 31
Complexity 1229.8622

Chemical Identifiers

CAS Number 161806-28-6
SMILES C1C(=O)N(C(=S)N(C1=O)/N=C/C=C/C2=CC=CC=C2)C(=O)CC3=CNC4=CC=CC=C43

Product Overview

1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid (CAS 161806-28-6), with molecular formula C23H18N4O3S and molecular weight 430.11 g/mol. IUPAC: 1-[2-(1H-indol-3-yl)acetyl]-3-[(E)-[(E)-3-phenylprop-2-enylidene]amino]-2-sulfanylidene-1,3-diazinane-4,6-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid

XLogP
3.282
TPSA (Topological Polar Surface Area)
85.84
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
31
Complexity
1229.8622
Exact Mass
430.10995
Monoisotopic Mass
430.10995
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid

The XLogP value of 3.282 indicates that 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.84 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid. Following Lipinski's Rule of Five, 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid?

The CAS number of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid is 161806-28-6.

What is the molecular formula of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid?

The molecular formula of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid is C23H18N4O3S.

What is the molecular weight of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid?

The molecular weight of 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid is 430.11 g/mol.

Where can I buy 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid?

You can request a quote for 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid?

Yes, KEHONG BIO provides custom synthesis services for 1-(Cinnamylideneamino)-3-(3-indolylacetyl)-2-thiobarbituric acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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