Spiroquinazoline structure

Spiroquinazoline

TL;DR: Spiroquinazoline (CAS 157075-58-6) is a chemical compound with molecular formula C23H19N5O3 and molecular weight 413.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

12-methylspiro[2,10,13-triazatetracyclo[10.2.2.02,11.04,9]hexadeca-4,6,8,10-tetraene-16,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,14-trione

Also Known As: Spiroquinazoline, J3.180.071D, 12-Methylspiro[2,10,13-triazatetracyclo[10.2.2.02,11.04,9]hexadeca-4,6,8,10-tetraene-16,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,14-trione, (1R-(1alpha,4alpha,13R*(S*)))-1',9'a-Dihydro-1-methylspiro(1,4-ethano-2H-pyrazino(2,1-b)quinazoline-13,9'-(9H)imidazo(1,2-a)indole)-3,3',6(1H,2'H,4H)-trione, 1',9'a-Dihydro-1-methylspiro(1,4-ethano-2H-pyrazino(2,1-b)quinazoline-13,9'-(9H)imidazo(1,2-a)indole)-3,3',6(1H,2'H,4H)-trione (1R-(1alpha,4alpha,13R*(S*)))-

CAS: 157075-58-6
Molecular Formula C23H19N5O3
Molecular Weight 413.15 g/mol
LogP 0.8
Topological Polar Surface Area 94.1 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 5
Rotatable Bonds 0
Exact Mass 413.1488
Heavy Atoms 31
Complexity 934.0

Chemical Identifiers

CAS Number 157075-58-6
SMILES CC12C3=NC4=CC=CC=C4C(=O)N3C(CC15C6NCC(=O)N6C7=CC=CC=C57)C(=O)N2
InChIKey SIIMITFGYHVBGG-UHFFFAOYSA-N

Product Overview

Spiroquinazoline (CAS 157075-58-6), with molecular formula C23H19N5O3 and molecular weight 413.15 g/mol. IUPAC: 12-methylspiro[2,10,13-triazatetracyclo[10.2.2.02,11.04,9]hexadeca-4,6,8,10-tetraene-16,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,14-trione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Spiroquinazoline

XLogP
0.8
TPSA (Topological Polar Surface Area)
94.1
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
5
Rotatable Bonds
0
Heavy Atoms
31
Complexity
934.0
Exact Mass
413.1488
Monoisotopic Mass
413.1488
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Spiroquinazoline

The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Spiroquinazoline. The TPSA of 94.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Spiroquinazoline. Following Lipinski's Rule of Five, Spiroquinazoline has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Spiroquinazoline?

The CAS number of Spiroquinazoline is 157075-58-6.

What is the molecular formula of Spiroquinazoline?

The molecular formula of Spiroquinazoline is C23H19N5O3.

What is the molecular weight of Spiroquinazoline?

The molecular weight of Spiroquinazoline is 413.15 g/mol.

Where can I buy Spiroquinazoline?

You can request a quote for Spiroquinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Spiroquinazoline?

Yes, KEHONG BIO provides custom synthesis services for Spiroquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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