Ap-1/nf-kappab dual inhibitor
TL;DR: Ap-1/nf-kappab dual inhibitor (CAS 154563-54-9) is a chemical compound with molecular formula C14H5ClF9N3O and molecular weight 437.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3,5-bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide
Also Known As: Ap-1/nf-kappab dual inhibitor, N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide, N-(3,5-Bis(trifluoromethyl)phenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide, N-[3,5-bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide, 2-Chloro-N-[3,5-bis(trifluoromethyl)phenyl]-4-(trifluoromethyl)pyrimidine-5-carboxamide
| Molecular Formula | C14H5ClF9N3O |
|---|---|
| Molecular Weight | 437.00 g/mol |
| LogP | 5.4387 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 436.99774 |
| Heavy Atoms | 28 |
| Complexity | 874.14594 |
Chemical Identifiers
| CAS Number | 154563-54-9 |
|---|---|
| SMILES | C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=CN=C(N=C2C(F)(F)F)Cl)C(F)(F)F |
Product Overview
Ap-1/nf-kappab dual inhibitor (CAS 154563-54-9), with molecular formula C14H5ClF9N3O and molecular weight 437.00 g/mol. IUPAC: N-[3,5-bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide.
Chemical Property Profile of Ap-1/nf-kappab dual inhibitor
Property Insights of Ap-1/nf-kappab dual inhibitor
The XLogP value of 5.4387 indicates that Ap-1/nf-kappab dual inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, Ap-1/nf-kappab dual inhibitor exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ap-1/nf-kappab dual inhibitor has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ap-1/nf-kappab dual inhibitor?
The CAS number of Ap-1/nf-kappab dual inhibitor is 154563-54-9.
What is the molecular formula of Ap-1/nf-kappab dual inhibitor?
The molecular formula of Ap-1/nf-kappab dual inhibitor is C14H5ClF9N3O.
What is the molecular weight of Ap-1/nf-kappab dual inhibitor?
The molecular weight of Ap-1/nf-kappab dual inhibitor is 437.00 g/mol.
Where can I buy Ap-1/nf-kappab dual inhibitor?
You can request a quote for Ap-1/nf-kappab dual inhibitor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ap-1/nf-kappab dual inhibitor?
Yes, KEHONG BIO provides custom synthesis services for Ap-1/nf-kappab dual inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.