![(2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile structure](/static/products/154/154365-94-3.png)
(2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile
TL;DR: (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile (CAS 154365-94-3) is a chemical compound with molecular formula C22H12Cl2N4OS and molecular weight 450.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2Z)-5-amino-7-(2-chlorophenyl)-2-[(2-chlorophenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile
Also Known As: (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile, (2Z)-5-amino-7-(2-chlorophenyl)-2-[(2-chlorophenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile, (Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-6,8-dicarbonitrile, 5-amino-7-(2-chlorophenyl)-2-[(2-chlorophenyl)methylene]-3-oxo-4,7-dihydro-1,3 -thiazolidino[3,2-a]pyridine-6,8-dicarbonitrile
| Molecular Formula | C22H12Cl2N4OS |
|---|---|
| Molecular Weight | 450.01 g/mol |
| LogP | 3.16796 |
| Topological Polar Surface Area | 95.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 450.0109 |
| Heavy Atoms | 30 |
| Complexity | 1484.7412 |
Chemical Identifiers
| CAS Number | 154365-94-3 |
|---|---|
| SMILES | C1=CC=C(C(=C1)/C=C\2/C(=O)N3C(=C(C(C(=C3S2)C#N)C4=CC=CC=C4Cl)C#N)N)Cl |
Product Overview
(2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile (CAS 154365-94-3), with molecular formula C22H12Cl2N4OS and molecular weight 450.01 g/mol. IUPAC: (2Z)-5-amino-7-(2-chlorophenyl)-2-[(2-chlorophenyl)methylidene]-3-oxo-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile.
Chemical Property Profile of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile
Property Insights of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile
The XLogP value of 3.16796 indicates that (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile. Following Lipinski's Rule of Five, (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile?
The CAS number of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile is 154365-94-3.
What is the molecular formula of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile?
The molecular formula of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile is C22H12Cl2N4OS.
What is the molecular weight of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile?
The molecular weight of (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile is 450.01 g/mol.
Where can I buy (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile?
You can request a quote for (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile?
Yes, KEHONG BIO provides custom synthesis services for (2Z)-5-amino-2-(2-chlorobenzylidene)-7-(2-chlorophenyl)-3-oxo-2,3-dihydro-7H-[1,3]thiazolo[3,2-a]pyridine-6,8-dicarbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.