RefChem:372162
TL;DR: RefChem:372162 (CAS 153804-54-7) is a chemical compound with molecular formula C22H27FN2OS and molecular weight 386.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-(3,4-dihydro-2H-thiochromen-8-yloxy)propyl]-4-(4-fluorophenyl)piperazine
Also Known As: 8-((3-(4-(4-Fluorophenyl)piperazin-1-yl)propyl)oxy)thiochroman, Piperazine, 1-(3-((3,4-dihydro-2H-1-benzothiopyran-8-yl)oxy)propyl)-4-(4-fluorophenyl)-, 1-(3-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)propyl)-4-(4-fluorophenyl)piperazine, 1-[3-(3,4-dihydro-2H-thiochromen-8-yloxy)propyl]-4-(4-fluorophenyl)piperazine, 1-{3-[(3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy]propyl}-4-(4-fluorophenyl)piperazine
| Molecular Formula | C22H27FN2OS |
|---|---|
| Molecular Weight | 386.18 g/mol |
| LogP | 4.4551 |
| Topological Polar Surface Area | 15.71 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 386.1828 |
| Heavy Atoms | 27 |
| Complexity | 744.478 |
Chemical Identifiers
| CAS Number | 153804-54-7 |
|---|---|
| SMILES | C1CC2=C(C(=CC=C2)OCCCN3CCN(CC3)C4=CC=C(C=C4)F)SC1 |
Product Overview
RefChem:372162 (CAS 153804-54-7), with molecular formula C22H27FN2OS and molecular weight 386.18 g/mol. IUPAC: 1-[3-(3,4-dihydro-2H-thiochromen-8-yloxy)propyl]-4-(4-fluorophenyl)piperazine.
Chemical Property Profile of RefChem:372162
Property Insights of RefChem:372162
The XLogP value of 4.4551 indicates that RefChem:372162 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.71 Ų, RefChem:372162 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:372162 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:372162?
The CAS number of RefChem:372162 is 153804-54-7.
What is the molecular formula of RefChem:372162?
The molecular formula of RefChem:372162 is C22H27FN2OS.
What is the molecular weight of RefChem:372162?
The molecular weight of RefChem:372162 is 386.18 g/mol.
Where can I buy RefChem:372162?
You can request a quote for RefChem:372162 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:372162?
Yes, KEHONG BIO provides custom synthesis services for RefChem:372162 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.