(-)-threo-Mefloquine
TL;DR: (-)-threo-Mefloquine (CAS 148690-80-6) is a chemical compound with molecular formula C17H16F6N2O and molecular weight 378.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(R)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol
Also Known As: (-)-Threo-Mefloquine, Threo-mefloquine, mefloquine, Lariam, (-)-anti-Mefloquine
| Molecular Formula | C17H16F6N2O |
|---|---|
| Molecular Weight | 378.12 g/mol |
| LogP | 4.4479 |
| Topological Polar Surface Area | 45.15 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.11667 |
| Heavy Atoms | 26 |
| Complexity | 796.1653 |
Chemical Identifiers
| CAS Number | 148690-80-6 |
|---|---|
| SMILES | C1CCN[C@H](C1)[C@@H](C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O |
Product Overview
(-)-threo-Mefloquine (CAS 148690-80-6), with molecular formula C17H16F6N2O and molecular weight 378.12 g/mol. IUPAC: (R)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol.
Chemical Property Profile of (-)-threo-Mefloquine
Property Insights of (-)-threo-Mefloquine
The XLogP value of 4.4479 indicates that (-)-threo-Mefloquine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.15 Ų, (-)-threo-Mefloquine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (-)-threo-Mefloquine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-threo-Mefloquine?
The CAS number of (-)-threo-Mefloquine is 148690-80-6.
What is the molecular formula of (-)-threo-Mefloquine?
The molecular formula of (-)-threo-Mefloquine is C17H16F6N2O.
What is the molecular weight of (-)-threo-Mefloquine?
The molecular weight of (-)-threo-Mefloquine is 378.12 g/mol.
Where can I buy (-)-threo-Mefloquine?
You can request a quote for (-)-threo-Mefloquine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-threo-Mefloquine?
Yes, KEHONG BIO provides custom synthesis services for (-)-threo-Mefloquine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.