Flumethiazide
TL;DR: Flumethiazide (CAS 148-56-1) is a chemical compound with molecular formula C8H6F3N3O4S2 and molecular weight 328.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1,1-dioxo-6-(trifluoromethyl)-4H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: FLUMETHIAZIDE, Ademol, Flumethiazid, Flumetiazid, Fludemil
| Molecular Formula | C8H6F3N3O4S2 |
|---|---|
| Molecular Weight | 328.98 g/mol |
| LogP | -0.2 |
| Topological Polar Surface Area | 135.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 1 |
| Exact Mass | 328.9752 |
| Heavy Atoms | 20 |
| Complexity | 617.0 |
| Solubility | SPARINGLY SOL IN WATER; 50 MG/ML IN BOILING WATER WITH DECOMP; PRACTICALLY INSOL IN ETHYL ACETATE, METHYL ETHYL KETONE, BENZENE, TOLUENE; SOL IN METHANOL, ETHANOL, DIMETHYL FORMAMIDE |
Chemical Identifiers
| CAS Number | 148-56-1 |
|---|---|
| SMILES | C1=C(C(=CC2=C1NC=NS2(=O)=O)S(=O)(=O)N)C(F)(F)F |
| InChIKey | RGUQWGXAYZNLMI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Flumethiazide (CAS 148-56-1), with molecular formula C8H6F3N3O4S2 and molecular weight 328.98 g/mol. IUPAC: 1,1-dioxo-6-(trifluoromethyl)-4H-1λ6,2,4-benzothiadiazine-7-sulfonamide.
Chemical Property Profile of Flumethiazide
Property Insights of Flumethiazide
The XLogP value of -0.2 indicates that Flumethiazide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 135.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Flumethiazide. Following Lipinski's Rule of Five, Flumethiazide has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Flumethiazide?
The CAS number of Flumethiazide is 148-56-1.
What is the molecular formula of Flumethiazide?
The molecular formula of Flumethiazide is C8H6F3N3O4S2.
What is the molecular weight of Flumethiazide?
The molecular weight of Flumethiazide is 328.98 g/mol.
Where can I buy Flumethiazide?
You can request a quote for Flumethiazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Flumethiazide?
Yes, KEHONG BIO provides custom synthesis services for Flumethiazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.