西立伐他汀
TL;DR: 西立伐他汀 (CAS 145599-86-6) is a chemical compound with molecular formula C26H34FNO5 and molecular weight 459.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
西立伐他汀
7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)-3-pyridinyl]-3,5-dihydroxyhept-6-enoic acid
Also Known As: cerivastatin, Cerivastatin, sodium salt, CERIVASTATIN LACTONE, 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid, BAY-w-6228; BAY-w 6228; BAY-w6228;Rivastatin
| Molecular Formula | C26H34FNO5 |
|---|---|
| Molecular Weight | 459.24 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 99.9 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 11 |
| Exact Mass | 459.2421 |
| Heavy Atoms | 33 |
| Complexity | 620.0 |
Chemical Identifiers
| CAS Number | 145599-86-6 |
|---|---|
| SMILES | CC(C)C1=C(C(=C(C(=N1)C(C)C)COC)C2=CC=C(C=C2)F)C=CC(CC(CC(=O)O)O)O |
| InChIKey | SEERZIQQUAZTOL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
西立伐他汀 (CAS 145599-86-6), with molecular formula C26H34FNO5 and molecular weight 459.24 g/mol. IUPAC: 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)-3-pyridinyl]-3,5-dihydroxyhept-6-enoic acid.
Chemical Property Profile of 西立伐他汀
Property Insights of 西立伐他汀
The XLogP value of 3.6 indicates that 西立伐他汀 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 西立伐他汀. Following Lipinski's Rule of Five, 西立伐他汀 has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 西立伐他汀?
The CAS number of 西立伐他汀 is 145599-86-6.
What is the molecular formula of 西立伐他汀?
The molecular formula of 西立伐他汀 is C26H34FNO5.
What is the molecular weight of 西立伐他汀?
The molecular weight of 西立伐他汀 is 459.24 g/mol.
Where can I buy 西立伐他汀?
You can request a quote for 西立伐他汀 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 西立伐他汀?
Yes, KEHONG BIO provides custom synthesis services for 西立伐他汀 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.