5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide structure

5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide

TL;DR: 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide (CAS 144462-46-4) is a chemical compound with molecular formula C3H3F3N4O4S3 and molecular weight 311.93 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide

Also Known As: NCI60_036195, 5-(trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide, J1.446.083G, 5-(trifluoromethanesulfonamido)-1,3,4-thiadiazole-2-sulfonamide, 1,3,4-Thiadiazole-2-sulfonamide, 5-[[(trifluoromethyl)sulfonyl]amino]-

CAS: 144462-46-4
Molecular Formula C3H3F3N4O4S3
Molecular Weight 311.93 g/mol
LogP 0.7
Topological Polar Surface Area 177.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 12
Rotatable Bonds 3
Exact Mass 311.92685
Heavy Atoms 17
Complexity 475.0

Chemical Identifiers

CAS Number 144462-46-4
SMILES C1(=NN=C(S1)S(=O)(=O)N)NS(=O)(=O)C(F)(F)F
InChIKey JHGJJWFACYMJQC-UHFFFAOYSA-N

Product Overview

5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide (CAS 144462-46-4), with molecular formula C3H3F3N4O4S3 and molecular weight 311.93 g/mol. IUPAC: 5-(trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide

XLogP
0.7
TPSA (Topological Polar Surface Area)
177.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
12
Rotatable Bonds
3
Heavy Atoms
17
Complexity
475.0
Exact Mass
311.92685
Monoisotopic Mass
311.92685
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide

The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide. The TPSA of 177.0 Ų indicates high polarity, suggesting 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide has 2 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide?

The CAS number of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide is 144462-46-4.

What is the molecular formula of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide?

The molecular formula of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide is C3H3F3N4O4S3.

What is the molecular weight of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide?

The molecular weight of 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide is 311.93 g/mol.

Where can I buy 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide?

You can request a quote for 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide?

Yes, KEHONG BIO provides custom synthesis services for 5-(Trifluoromethylsulfonylamino)-1,3,4-thiadiazole-2-sulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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