Rofleponide
TL;DR: Rofleponide (CAS 144459-70-1) is a chemical compound with molecular formula C25H34F2O6 and molecular weight 468.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,2S,4R,6R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one
Also Known As: Rofleponide, rofleponida, Rofleponide [INN], rofleponidum, (1S,2S,4R,6R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one
| Molecular Formula | C25H34F2O6 |
|---|---|
| Molecular Weight | 468.23 g/mol |
| LogP | 2.9809 |
| Topological Polar Surface Area | 93.06 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 468.23233 |
| Heavy Atoms | 33 |
| Complexity | 907.328 |
Chemical Identifiers
| CAS Number | 144459-70-1 |
|---|---|
| SMILES | CCC[C@@H]1O[C@@H]2C[C@H]3[C@@H]4C[C@@H](C5=CC(=O)CC[C@@]5([C@]4([C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)F)C)F |
Product Overview
Rofleponide (CAS 144459-70-1), with molecular formula C25H34F2O6 and molecular weight 468.23 g/mol. IUPAC: (1S,2S,4R,6R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one.
Chemical Property Profile of Rofleponide
Property Insights of Rofleponide
The XLogP value of 2.9809 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Rofleponide. The TPSA of 93.06 Ų falls within the moderate polarity range, balancing permeability and solubility for Rofleponide. Following Lipinski's Rule of Five, Rofleponide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Rofleponide?
The CAS number of Rofleponide is 144459-70-1.
What is the molecular formula of Rofleponide?
The molecular formula of Rofleponide is C25H34F2O6.
What is the molecular weight of Rofleponide?
The molecular weight of Rofleponide is 468.23 g/mol.
Where can I buy Rofleponide?
You can request a quote for Rofleponide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Rofleponide?
Yes, KEHONG BIO provides custom synthesis services for Rofleponide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.