6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin structure

6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin

TL;DR: 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin (CAS 144363-91-7) is a chemical compound with molecular formula C216H402N16O173 and molecular weight 5988.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

tetrakis(3-(2-methylpropyl)-6-[[1-[[36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecahydroxy-10,15,20,25,30,35-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontan-5-yl]methyl]imidazol-4-yl]methyl]piperazine-2,5-dione);nonacosahydrate

Also Known As: Chl-betacd, 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin, C54H86N4O36.29/4H2O, 6-Deoxy-6-cyclo(L-his-L-leu)-beta-cyclodextrin, hydrate (4:29), C54-H86-N4-O36.29/4H2-O

CAS: 144363-91-7
Molecular Formula C216H402N16O173
Molecular Weight 5988.31 g/mol
LogP -82.9339
Topological Polar Surface Area 3352.86 Ų
Hydrogen Bond Donors 88
Hydrogen Bond Acceptors 148
Rotatable Bonds 48
Exact Mass 5988.315
Heavy Atoms 405
Complexity 11761.325

Chemical Identifiers

CAS Number 144363-91-7
SMILES CC(C)CC1C(=O)NC(C(=O)N1)CC2=CN(C=N2)CC3C4C(C(C(O3)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(C(C8O)O)OC9C(OC(C(C9O)O)OC1C(OC(O4)C(C1O)O)CO)CO)CO)CO)CO)CO)O)O.CC(C)CC1C(=O)NC(C(=O)N1)CC2=CN(C=N2)CC3C4C(C(C(O3)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(C(C8O)O)OC9C(OC(C(C9O)O)OC1C(OC(O4)C(C1O)O)CO)CO)CO)CO)CO)CO)O)O.CC(C)CC1C(=O)NC(C(=O)N1)CC2=CN(C=N2)CC3C4C(C(C(O3)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(C(C8O)O)OC9C(OC(C(C9O)O)OC1C(OC(O4)C(C1O)O)CO)CO)CO)CO)CO)CO)O)O.CC(C)CC1C(=O)NC(C(=O)N1)CC2=CN(C=N2)CC3C4C(C(C(O3)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(C(C8O)O)OC9C(OC(C(C9O)O)OC1C(OC(O4)C(C1O)O)CO)CO)CO)CO)CO)CO)O)O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O

Product Overview

6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin (CAS 144363-91-7), with molecular formula C216H402N16O173 and molecular weight 5988.31 g/mol. IUPAC: tetrakis(3-(2-methylpropyl)-6-[[1-[[36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecahydroxy-10,15,20,25,30,35-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontan-5-yl]methyl]imidazol-4-yl]methyl]piperazine-2,5-dione);nonacosahydrate.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin

XLogP
-82.9339
TPSA (Topological Polar Surface Area)
3352.86
Hydrogen Bond Donors
88
Hydrogen Bond Acceptors
148
Rotatable Bonds
48
Heavy Atoms
405
Complexity
11761.325
Exact Mass
5988.315
Monoisotopic Mass
5990.322
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin

The XLogP value of -82.9339 indicates that 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 3352.86 Ų indicates high polarity, suggesting 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin has 88 hydrogen bond donor(s) and 148 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
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Frequently Asked Questions

What is the CAS number of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin?

The CAS number of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin is 144363-91-7.

What is the molecular formula of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin?

The molecular formula of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin is C216H402N16O173.

What is the molecular weight of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin?

The molecular weight of 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin is 5988.31 g/mol.

Where can I buy 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin?

You can request a quote for 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin?

Yes, KEHONG BIO provides custom synthesis services for 6-Deoxy-6-cyclo(histidyl-leucyl)cyclodextrin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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