Bms 180448
TL;DR: Bms 180448 (CAS 144264-47-1) is a chemical compound with molecular formula C20H18ClN5O2 and molecular weight 395.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-chlorophenyl)-3-cyano-2-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]guanidine
Also Known As: Bms 180426, Guanidine, N-(4-chlorophenyl)-N'-cyano-N''-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-, trans-, 1-(4-chlorophenyl)-3-cyano-2-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]guanidine, trans-N-(4-Chlorophenyl)-N'-cyano-N''-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)guanidine, 1-(4-chlorophenyl)-3-cyano-2-[(3R,4S)-6-cyano-3-hydroxy-2,2-
| Molecular Formula | C20H18ClN5O2 |
|---|---|
| Molecular Weight | 395.11 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 113.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 395.1149 |
| Heavy Atoms | 28 |
| Complexity | 685.0 |
Chemical Identifiers
| CAS Number | 144264-47-1 |
|---|---|
| SMILES | CC1([C@@H]([C@H](C2=C(O1)C=CC(=C2)C#N)N=C(NC#N)NC3=CC=C(C=C3)Cl)O)C |
| InChIKey | VLICJSLDCJXZBG-ZWKOTPCHSA-N |
Product Overview
Bms 180448 (CAS 144264-47-1), with molecular formula C20H18ClN5O2 and molecular weight 395.11 g/mol. IUPAC: 1-(4-chlorophenyl)-3-cyano-2-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]guanidine.
Chemical Property Profile of Bms 180448
Property Insights of Bms 180448
The XLogP value of 3.4 indicates that Bms 180448 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Bms 180448. Following Lipinski's Rule of Five, Bms 180448 has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bms 180448?
The CAS number of Bms 180448 is 144264-47-1.
What is the molecular formula of Bms 180448?
The molecular formula of Bms 180448 is C20H18ClN5O2.
What is the molecular weight of Bms 180448?
The molecular weight of Bms 180448 is 395.11 g/mol.
Where can I buy Bms 180448?
You can request a quote for Bms 180448 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bms 180448?
Yes, KEHONG BIO provides custom synthesis services for Bms 180448 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.