利瑞喹尼
TL;DR: 利瑞喹尼 (CAS 143943-73-1) is a chemical compound with molecular formula C26H25ClN2O3 and molecular weight 448.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
利瑞喹尼
10-chloro-1-[(3S)-3-ethoxypyrrolidine-1-carbonyl]-3-phenyl-6,7-dihydrobenzo[a]quinolizin-4-one
Also Known As: Lirequinil, Lirequinilo, Lirequinil [INN], Ro-41-3696, 10-chloro-1-[(3S)-3-ethoxypyrrolidine-1-carbonyl]-3-phenyl-6,7-dihydrobenzo[a]quinolizin-4-one
| Molecular Formula | C26H25ClN2O3 |
|---|---|
| Molecular Weight | 448.16 g/mol |
| LogP | 4.6428 |
| Topological Polar Surface Area | 51.54 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 448.15536 |
| Heavy Atoms | 32 |
| Complexity | 1235.8097 |
Chemical Identifiers
| CAS Number | 143943-73-1 |
|---|---|
| SMILES | CCO[C@H]1CCN(C1)C(=O)C2=C3C4=C(CCN3C(=O)C(=C2)C5=CC=CC=C5)C=CC(=C4)Cl |
Product Overview
利瑞喹尼 (CAS 143943-73-1), with molecular formula C26H25ClN2O3 and molecular weight 448.16 g/mol. IUPAC: 10-chloro-1-[(3S)-3-ethoxypyrrolidine-1-carbonyl]-3-phenyl-6,7-dihydrobenzo[a]quinolizin-4-one.
Chemical Property Profile of 利瑞喹尼
Property Insights of 利瑞喹尼
The XLogP value of 4.6428 indicates that 利瑞喹尼 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.54 Ų, 利瑞喹尼 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 利瑞喹尼 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 利瑞喹尼?
The CAS number of 利瑞喹尼 is 143943-73-1.
What is the molecular formula of 利瑞喹尼?
The molecular formula of 利瑞喹尼 is C26H25ClN2O3.
What is the molecular weight of 利瑞喹尼?
The molecular weight of 利瑞喹尼 is 448.16 g/mol.
Where can I buy 利瑞喹尼?
You can request a quote for 利瑞喹尼 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 利瑞喹尼?
Yes, KEHONG BIO provides custom synthesis services for 利瑞喹尼 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.