4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid
TL;DR: 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid (CAS 141901-74-8) is a chemical compound with molecular formula C22H17F3O3 and molecular weight 386.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-hydroxy-2-(2-phenylphenyl)-3-[4-(trifluoromethyl)phenyl]propanoic acid
Also Known As: 4-Tmbpa, 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid, 3-hydroxy-2-(2-phenylphenyl)-3-[4-(trifluoromethyl)phenyl]propanoic acid, 4-trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionicacid, 2-([1,1'-Biphenyl]-2-yl)-3-hydroxy-3-[4-(trifluoromethyl)phenyl]propanoic acid
| Molecular Formula | C22H17F3O3 |
|---|---|
| Molecular Weight | 386.11 g/mol |
| LogP | 4.5 |
| Topological Polar Surface Area | 57.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 386.11298 |
| Heavy Atoms | 28 |
| Complexity | 508.0 |
Chemical Identifiers
| CAS Number | 141901-74-8 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=CC=CC=C2C(C(C3=CC=C(C=C3)C(F)(F)F)O)C(=O)O |
| InChIKey | WZCPXDVHGSRSLT-UHFFFAOYSA-N |
Product Overview
4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid (CAS 141901-74-8), with molecular formula C22H17F3O3 and molecular weight 386.11 g/mol. IUPAC: 3-hydroxy-2-(2-phenylphenyl)-3-[4-(trifluoromethyl)phenyl]propanoic acid.
Chemical Property Profile of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid
Property Insights of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid
The XLogP value of 4.5 indicates that 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.5 Ų, 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid?
The CAS number of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid is 141901-74-8.
What is the molecular formula of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid?
The molecular formula of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid is C22H17F3O3.
What is the molecular weight of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid?
The molecular weight of 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid is 386.11 g/mol.
Where can I buy 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid?
You can request a quote for 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid?
Yes, KEHONG BIO provides custom synthesis services for 4-Trifluoromethylphenyl-2-biphenylyl-3-hydroxypropionic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.