Tyrphostin AG 537
TL;DR: Tyrphostin AG 537 (CAS 140674-77-7) is a chemical compound with molecular formula C23H20N4O6 and molecular weight 448.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-N-[3-[[(E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]propyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide
Also Known As: Tyrphostin AG 537, bis-tyrphostin, Dimeric Tyrphostin 2, Lopac-T-4693, Lopac0_001148
| Molecular Formula | C23H20N4O6 |
|---|---|
| Molecular Weight | 448.14 g/mol |
| LogP | 1.64566 |
| Topological Polar Surface Area | 186.7 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 448.13828 |
| Heavy Atoms | 33 |
| Complexity | 1110.908 |
Chemical Identifiers
| CAS Number | 140674-77-7 |
|---|---|
| SMILES | C1=CC(=C(C=C1/C=C(/C(=O)NCCCNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N)\C#N)O)O |
Product Overview
Tyrphostin AG 537 (CAS 140674-77-7), with molecular formula C23H20N4O6 and molecular weight 448.14 g/mol. IUPAC: (E)-2-cyano-N-[3-[[(E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]propyl]-3-(3,4-dihydroxyphenyl)prop-2-enamide.
Chemical Property Profile of Tyrphostin AG 537
Property Insights of Tyrphostin AG 537
The XLogP value of 1.64566 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tyrphostin AG 537. The TPSA of 186.7 Ų indicates high polarity, suggesting Tyrphostin AG 537 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tyrphostin AG 537 has 6 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tyrphostin AG 537?
The CAS number of Tyrphostin AG 537 is 140674-77-7.
What is the molecular formula of Tyrphostin AG 537?
The molecular formula of Tyrphostin AG 537 is C23H20N4O6.
What is the molecular weight of Tyrphostin AG 537?
The molecular weight of Tyrphostin AG 537 is 448.14 g/mol.
Where can I buy Tyrphostin AG 537?
You can request a quote for Tyrphostin AG 537 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tyrphostin AG 537?
Yes, KEHONG BIO provides custom synthesis services for Tyrphostin AG 537 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.