两性霉素B
TL;DR: 两性霉素B (CAS 1397-89-3) is a chemical compound with molecular formula C47H73NO17 and molecular weight 923.49 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
两性霉素B
33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Also Known As: amphotericin b, Fungizone, Ambisome, Amphozone, Fungilin
| Molecular Formula | C47H73NO17 |
|---|---|
| Molecular Weight | 923.49 g/mol |
| LogP | 0.0 |
| Topological Polar Surface Area | 320.0 Ų |
| Hydrogen Bond Donors | 12 |
| Hydrogen Bond Acceptors | 18 |
| Rotatable Bonds | 3 |
| Exact Mass | 923.48785 |
| Heavy Atoms | 65 |
| Complexity | 1670.0 |
Chemical Identifiers
| CAS Number | 1397-89-3 |
|---|---|
| SMILES | CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O |
| InChIKey | APKFDSVGJQXUKY-UHFFFAOYSA-N |
Product Overview
两性霉素B (CAS 1397-89-3), with molecular formula C47H73NO17 and molecular weight 923.49 g/mol. IUPAC: 33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid.
Chemical Property Profile of 两性霉素B
Property Insights of 两性霉素B
The XLogP value of 0.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 两性霉素B. The TPSA of 320.0 Ų indicates high polarity, suggesting 两性霉素B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 两性霉素B has 12 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 两性霉素B?
The CAS number of 两性霉素B is 1397-89-3.
What is the molecular formula of 两性霉素B?
The molecular formula of 两性霉素B is C47H73NO17.
What is the molecular weight of 两性霉素B?
The molecular weight of 两性霉素B is 923.49 g/mol.
Where can I buy 两性霉素B?
You can request a quote for 两性霉素B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 两性霉素B?
Yes, KEHONG BIO provides custom synthesis services for 两性霉素B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.