Camptothecin-20-O-propionate
TL;DR: Camptothecin-20-O-propionate (CAS 1374663-29-2) is a chemical compound with molecular formula C23H20N2O5 and molecular weight 404.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(19S)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] propanoate
Also Known As: Camptothecin-20(S)-O-propionate, Camptothecin-20-O-propionate, Sulfo-ara-F-NMN, SF 6A, SF-6A
| Molecular Formula | C23H20N2O5 |
|---|---|
| Molecular Weight | 404.14 g/mol |
| LogP | 3.0405 |
| Topological Polar Surface Area | 87.49 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 404.1372 |
| Heavy Atoms | 30 |
| Complexity | 1292.7285 |
Chemical Identifiers
| CAS Number | 1374663-29-2 |
|---|---|
| SMILES | CCC(=O)O[C@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)CC |
Product Overview
Camptothecin-20-O-propionate (CAS 1374663-29-2), with molecular formula C23H20N2O5 and molecular weight 404.14 g/mol. IUPAC: [(19S)-19-ethyl-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-19-yl] propanoate.
Chemical Property Profile of Camptothecin-20-O-propionate
Property Insights of Camptothecin-20-O-propionate
The XLogP value of 3.0405 indicates that Camptothecin-20-O-propionate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 87.49 Ų falls within the moderate polarity range, balancing permeability and solubility for Camptothecin-20-O-propionate. Following Lipinski's Rule of Five, Camptothecin-20-O-propionate has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Camptothecin-20-O-propionate?
The CAS number of Camptothecin-20-O-propionate is 1374663-29-2.
What is the molecular formula of Camptothecin-20-O-propionate?
The molecular formula of Camptothecin-20-O-propionate is C23H20N2O5.
What is the molecular weight of Camptothecin-20-O-propionate?
The molecular weight of Camptothecin-20-O-propionate is 404.14 g/mol.
Where can I buy Camptothecin-20-O-propionate?
You can request a quote for Camptothecin-20-O-propionate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Camptothecin-20-O-propionate?
Yes, KEHONG BIO provides custom synthesis services for Camptothecin-20-O-propionate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.