Perifosine
TL;DR: Perifosine (CAS 137281-23-3) is a chemical compound with molecular formula C25H52NO4P and molecular weight 461.36 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1,1-dimethylpiperidin-1-ium-4-yl) octadecyl phosphate
Also Known As: Perifosine, perifosina, perifosinum, Pemetrexed, Perifosine [INN]
| Molecular Formula | C25H52NO4P |
|---|---|
| Molecular Weight | 461.36 g/mol |
| LogP | 8.3 |
| Topological Polar Surface Area | 58.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 20 |
| Exact Mass | 461.3634 |
| Heavy Atoms | 31 |
| Complexity | 454.0 |
Chemical Identifiers
| CAS Number | 137281-23-3 |
|---|---|
| SMILES | CCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C |
| InChIKey | SZFPYBIJACMNJV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Perifosine (CAS 137281-23-3), with molecular formula C25H52NO4P and molecular weight 461.36 g/mol. IUPAC: (1,1-dimethylpiperidin-1-ium-4-yl) octadecyl phosphate.
Chemical Property Profile of Perifosine
Property Insights of Perifosine
The XLogP value of 8.3 indicates that Perifosine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.6 Ų, Perifosine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Perifosine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Perifosine?
The CAS number of Perifosine is 137281-23-3.
What is the molecular formula of Perifosine?
The molecular formula of Perifosine is C25H52NO4P.
What is the molecular weight of Perifosine?
The molecular weight of Perifosine is 461.36 g/mol.
Where can I buy Perifosine?
You can request a quote for Perifosine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Perifosine?
Yes, KEHONG BIO provides custom synthesis services for Perifosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.