丁酸氢化可的松
TL;DR: 丁酸氢化可的松 (CAS 13609-67-1) is a chemical compound with molecular formula C25H36O6 and molecular weight 432.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
丁酸氢化可的松
[11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate
Also Known As: Locoid, hydrocortisone butyrate, Hydrocortisone 17-butyrate, 4CA-0622, I06-0576
| Molecular Formula | C25H36O6 |
|---|---|
| Molecular Weight | 432.25 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 432.2512 |
| Heavy Atoms | 31 |
| Complexity | 817.0 |
Chemical Identifiers
| CAS Number | 13609-67-1 |
|---|---|
| SMILES | CCCC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)C(=O)CO |
| InChIKey | BMCQMVFGOVHVNG-UHFFFAOYSA-N |
Product Overview
丁酸氢化可的松 (CAS 13609-67-1), with molecular formula C25H36O6 and molecular weight 432.25 g/mol. IUPAC: [11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate.
Chemical Property Profile of 丁酸氢化可的松
Property Insights of 丁酸氢化可的松
The XLogP value of 3.2 indicates that 洛考特 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 丁酸氢化可的松. Following Lipinski's Rule of Five, 洛考特 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛考特?
The CAS number of 洛考特 is 13609-67-1.
What is the molecular formula of 洛考特?
The molecular formula of 洛考特 is C25H36O6.
What is the molecular weight of 洛考特?
The molecular weight of 洛考特 is 432.25 g/mol.
Where can I buy 洛考特?
You can request a quote for 洛考特 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛考特?
Yes, KEHONG BIO provides custom synthesis services for 洛考特 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.