Thiamine Pyrophosphate structure

Thiamine Pyrophosphate

TL;DR: Thiamine Pyrophosphate (CAS 136-09-4) is a chemical compound with molecular formula C12H18N4O7P2S and molecular weight 424.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethoxy-hydroxyphosphoryl] hydrogen phosphate

Also Known As: Thiamine pyrophosphate, cocarboxylase, thiamin pyrophosphate, Berolase, thiamine diphosphate

CAS: 136-09-4
Molecular Formula C12H18N4O7P2S
Molecular Weight 424.04 g/mol
LogP -1.2
Topological Polar Surface Area 200.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 11
Rotatable Bonds 8
Exact Mass 424.03714
Heavy Atoms 26
Complexity 565.0

Chemical Identifiers

CAS Number 136-09-4
SMILES CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)[O-]
InChIKey AYEKOFBPNLCAJY-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Analytical Reagents (18 patents) Biotechnology (69 patents) Catalysts (3 patents) Food Additives (2 patents) +3 more

Product Overview

Thiamine Pyrophosphate (CAS 136-09-4), with molecular formula C12H18N4O7P2S and molecular weight 424.04 g/mol. IUPAC: [2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethoxy-hydroxyphosphoryl] hydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thiamine Pyrophosphate

XLogP
-1.2
TPSA (Topological Polar Surface Area)
200.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
11
Rotatable Bonds
8
Heavy Atoms
26
Complexity
565.0
Exact Mass
424.03714
Monoisotopic Mass
424.03714
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thiamine Pyrophosphate

The XLogP value of -1.2 indicates that Thiamine Pyrophosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 200.0 Ų indicates high polarity, suggesting Thiamine Pyrophosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thiamine Pyrophosphate has 3 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thiamine Pyrophosphate?

The CAS number of Thiamine Pyrophosphate is 136-09-4.

What is the molecular formula of Thiamine Pyrophosphate?

The molecular formula of Thiamine Pyrophosphate is C12H18N4O7P2S.

What is the molecular weight of Thiamine Pyrophosphate?

The molecular weight of Thiamine Pyrophosphate is 424.04 g/mol.

Where can I buy Thiamine Pyrophosphate?

You can request a quote for Thiamine Pyrophosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thiamine Pyrophosphate?

Yes, KEHONG BIO provides custom synthesis services for Thiamine Pyrophosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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