10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid structure

10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid

TL;DR: 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid (CAS 135423-85-7) is a chemical compound with molecular formula C24H25N7O5 and molecular weight 491.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[[4-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid

Also Known As: 10-Pmdap, 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid, (2S)-2-[[4-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid, (2S)-2-({4-[({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl}methyl)(prop-2-yn-1-yl)amino]phenyl}formamido)pentanedioic acid, (S)-2-[4-[N-[[(2,4-Diamino-5-methylpyrido[2,3-d]pyrimidin)-6-yl]methyl]-N-(2-propynyl)amino]benzoylamino]glutaric acid

CAS: 135423-85-7
Molecular Formula C24H25N7O5
Molecular Weight 491.19 g/mol
LogP 1.0
Topological Polar Surface Area 198.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 11
Rotatable Bonds 10
Exact Mass 491.1917
Heavy Atoms 36
Complexity 840.0

Chemical Identifiers

CAS Number 135423-85-7
SMILES CC1=C2C(=NC(=NC2=NC=C1CN(CC#C)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)N)N
InChIKey NXZWILPVWKKBOG-KRWDZBQOSA-N

Product Overview

10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid (CAS 135423-85-7), with molecular formula C24H25N7O5 and molecular weight 491.19 g/mol. IUPAC: (2S)-2-[[4-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid

XLogP
1.0
TPSA (Topological Polar Surface Area)
198.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
11
Rotatable Bonds
10
Heavy Atoms
36
Complexity
840.0
Exact Mass
491.1917
Monoisotopic Mass
491.1917
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid

The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid. The TPSA of 198.0 Ų indicates high polarity, suggesting 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid has 5 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
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Frequently Asked Questions

What is the CAS number of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid?

The CAS number of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid is 135423-85-7.

What is the molecular formula of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid?

The molecular formula of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid is C24H25N7O5.

What is the molecular weight of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid?

The molecular weight of 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid is 491.19 g/mol.

Where can I buy 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid?

You can request a quote for 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid?

Yes, KEHONG BIO provides custom synthesis services for 10-Propargyl-5-methyl-5-deazaaminopterin analog of folic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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