Clevidipine
TL;DR: Clevidipine (CAS 1346602-00-3) is a chemical compound with molecular formula C21H23Cl2NO6 and molecular weight 455.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-(butanoyloxymethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Clevidipine, Cleviprex, Clevidipine butyrate, Clevelox, Clevidepine
| Molecular Formula | C21H23Cl2NO6 |
|---|---|
| Molecular Weight | 455.09 g/mol |
| LogP | 4.3 |
| Topological Polar Surface Area | 90.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 10 |
| Exact Mass | 455.09024 |
| Heavy Atoms | 30 |
| Complexity | 748.0 |
Chemical Identifiers
| CAS Number | 1346602-00-3 |
|---|---|
| SMILES | CCCC(=O)OCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C |
| InChIKey | KPBZROQVTHLCDU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Clevidipine (CAS 1346602-00-3), with molecular formula C21H23Cl2NO6 and molecular weight 455.09 g/mol. IUPAC: 5-O-(butanoyloxymethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Clevidipine
Property Insights of Clevidipine
The XLogP value of 4.3 indicates that Clevidipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Clevidipine. Following Lipinski's Rule of Five, Clevidipine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clevidipine?
The CAS number of Clevidipine is 1346602-00-3.
What is the molecular formula of Clevidipine?
The molecular formula of Clevidipine is C21H23Cl2NO6.
What is the molecular weight of Clevidipine?
The molecular weight of Clevidipine is 455.09 g/mol.
Where can I buy Clevidipine?
You can request a quote for Clevidipine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clevidipine?
Yes, KEHONG BIO provides custom synthesis services for Clevidipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.