(E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one
TL;DR: (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one (CAS 1322229-29-7) is a chemical compound with molecular formula C25H18BrNO3 and molecular weight 459.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-bromo-3-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one
Also Known As: BAS 00108197, (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one, 6-Bromo-3-[3-(3-methoxy-phenyl)-acryloyl]-4-phenyl-1H-quinolin-2-one, 3-[(2E)-3-(3-methoxyphenyl)prop-2-enoyl]-6-bromo-4-phenylhydroquinolin-2-one, 6-bromo-3-[(2E)-3-(3-methoxyphenyl)prop-2-enoyl]-4-phenylquinolin-2(1H)-one
| Molecular Formula | C25H18BrNO3 |
|---|---|
| Molecular Weight | 459.05 g/mol |
| LogP | 5.8623 |
| Topological Polar Surface Area | 59.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 459.047 |
| Heavy Atoms | 30 |
| Complexity | 1323.5579 |
Chemical Identifiers
| CAS Number | 1322229-29-7 |
|---|---|
| SMILES | COC1=CC=CC(=C1)/C=C/C(=O)C2=C(C3=C(C=CC(=C3)Br)NC2=O)C4=CC=CC=C4 |
Product Overview
(E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one (CAS 1322229-29-7), with molecular formula C25H18BrNO3 and molecular weight 459.05 g/mol. IUPAC: 6-bromo-3-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one.
Chemical Property Profile of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one
Property Insights of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one
The XLogP value of 5.8623 indicates that (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.16 Ų, (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one?
The CAS number of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one is 1322229-29-7.
What is the molecular formula of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one?
The molecular formula of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one is C25H18BrNO3.
What is the molecular weight of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one?
The molecular weight of (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one is 459.05 g/mol.
Where can I buy (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one?
You can request a quote for (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-6-bromo-3-(3-(3-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.