氯苯那敏
TL;DR: 氯苯那敏 (CAS 132-22-9) is a chemical compound with molecular formula C16H19ClN2 and molecular weight 274.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氯苯那敏
3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
Also Known As: chlorpheniramine, Chlorphenamine, Haynon, Clorfeniramina, Clorfenamina
| Molecular Formula | C16H19ClN2 |
|---|---|
| Molecular Weight | 274.12 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 16.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 274.1237 |
| Heavy Atoms | 19 |
| Complexity | 249.0 |
| Melting Point | 130 - 135 °C |
| Boiling Point | 142 |
| Solubility | 5500 |
| Refractive Index | BOX LIKE PRISMS & IRREGULAR FRAGMENTS; 1.533 (ALPHA); 1.668 (BETA; INTERMEDIATE INDEX); LESS THAN 1.734 (GAMMA; INCLINED) /MALEATE/ |
Chemical Identifiers
| CAS Number | 132-22-9 |
|---|---|
| SMILES | CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 |
| InChIKey | SOYKEARSMXGVTM-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 20 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
氯苯那敏 (CAS 132-22-9), with molecular formula C16H19ClN2 and molecular weight 274.12 g/mol. IUPAC: 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine.
Chemical Property Profile of 氯苯那敏
Property Insights of 氯苯那敏
The XLogP value of 3.4 indicates that 氯苯那敏 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 16.1 Ų, 氯苯那敏 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 氯苯那敏 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氯苯那敏?
The CAS number of 氯苯那敏 is 132-22-9.
What is the molecular formula of 氯苯那敏?
The molecular formula of 氯苯那敏 is C16H19ClN2.
What is the molecular weight of 氯苯那敏?
The molecular weight of 氯苯那敏 is 274.12 g/mol.
Where can I buy 氯苯那敏?
You can request a quote for 氯苯那敏 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氯苯那敏?
Yes, KEHONG BIO provides custom synthesis services for 氯苯那敏 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.