BIM-XI
TL;DR: BIM-XI (CAS 131848-98-1) is a chemical compound with molecular formula C28H28N4O2 and molecular weight 452.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
BIM-XI
3-[8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
Also Known As: BIM-XI, Bisindolylmaleimide XI, Ro 31-8830, Bisindolylmaleimide deriv. 18b, BIM11
| Molecular Formula | C28H28N4O2 |
|---|---|
| Molecular Weight | 452.22 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 59.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 452.22122 |
| Heavy Atoms | 34 |
| Complexity | 868.0 |
Chemical Identifiers
| CAS Number | 131848-98-1 |
|---|---|
| SMILES | CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN(C)C |
| InChIKey | FXGHOAZJQNLNFD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
BIM-XI (CAS 131848-98-1), with molecular formula C28H28N4O2 and molecular weight 452.22 g/mol. IUPAC: 3-[8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione.
Chemical Property Profile of BIM-XI
Property Insights of BIM-XI
The XLogP value of 3.4 indicates that BIM-XI is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.3 Ų, BIM-XI exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, BIM-XI has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of BIM-XI?
The CAS number of BIM-XI is 131848-98-1.
What is the molecular formula of BIM-XI?
The molecular formula of BIM-XI is C28H28N4O2.
What is the molecular weight of BIM-XI?
The molecular weight of BIM-XI is 452.22 g/mol.
Where can I buy BIM-XI?
You can request a quote for BIM-XI directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for BIM-XI?
Yes, KEHONG BIO provides custom synthesis services for BIM-XI and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.