(E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea
TL;DR: (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea (CAS 1313614-48-0) is a chemical compound with molecular formula C18H16N4OS and molecular weight 336.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-methylphenyl)-3-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]urea
Also Known As: (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea, 1-(4-methylphenyl)-3-[(2Z)-5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2(3H)-ylidene]urea, 1-(4-methylphenyl)-3-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]urea
| Molecular Formula | C18H16N4OS |
|---|---|
| Molecular Weight | 336.10 g/mol |
| LogP | 4.66092 |
| Topological Polar Surface Area | 66.91 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 336.1045 |
| Heavy Atoms | 24 |
| Complexity | 840.97003 |
Chemical Identifiers
| CAS Number | 1313614-48-0 |
|---|---|
| SMILES | CC1=CC=C(C=C1)NC(=O)NC2=NN=C(S2)/C=C/C3=CC=CC=C3 |
Product Overview
(E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea (CAS 1313614-48-0), with molecular formula C18H16N4OS and molecular weight 336.10 g/mol. IUPAC: 1-(4-methylphenyl)-3-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]urea.
Chemical Property Profile of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea
Property Insights of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea
The XLogP value of 4.66092 indicates that (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.91 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea. Following Lipinski's Rule of Five, (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea?
The CAS number of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea is 1313614-48-0.
What is the molecular formula of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea?
The molecular formula of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea is C18H16N4OS.
What is the molecular weight of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea?
The molecular weight of (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea is 336.10 g/mol.
Where can I buy (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea?
You can request a quote for (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea?
Yes, KEHONG BIO provides custom synthesis services for (E)-1-(5-styryl-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.