2-(4-Chlorophenyl)-2,2-difluoroacetic acid
TL;DR: 2-(4-Chlorophenyl)-2,2-difluoroacetic acid (CAS 130754-19-7) is a chemical compound with molecular formula C8H5ClF2O2 and molecular weight 205.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-chlorophenyl)-2,2-difluoroacetic acid
Also Known As: 2-(4-chlorophenyl)-2,2-difluoroacetic acid, (4-Chlorophenyl)-difluoroacetic acid, (4-chlorophenyl)(difluoro)acetic acid, (4-Chlorophenyl)di(fluoro)acetic acid, 2-(4-Chlorophenyl)-2,2-difluoroaceticacid
| Molecular Formula | C8H5ClF2O2 |
|---|---|
| Molecular Weight | 205.99 g/mol |
| LogP | 2.5164 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 205.99461 |
| Heavy Atoms | 13 |
| Complexity | 321.42084 |
Chemical Identifiers
| CAS Number | 130754-19-7 |
|---|---|
| SMILES | C1=CC(=CC=C1C(C(=O)O)(F)F)Cl |
Product Overview
2-(4-Chlorophenyl)-2,2-difluoroacetic acid (CAS 130754-19-7), with molecular formula C8H5ClF2O2 and molecular weight 205.99 g/mol. IUPAC: 2-(4-chlorophenyl)-2,2-difluoroacetic acid.
Chemical Property Profile of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid
Property Insights of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid
The XLogP value of 2.5164 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(4-Chlorophenyl)-2,2-difluoroacetic acid. With a topological polar surface area (TPSA) of 37.3 Ų, 2-(4-Chlorophenyl)-2,2-difluoroacetic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Chlorophenyl)-2,2-difluoroacetic acid has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid?
The CAS number of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid is 130754-19-7.
What is the molecular formula of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid?
The molecular formula of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid is C8H5ClF2O2.
What is the molecular weight of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid?
The molecular weight of 2-(4-Chlorophenyl)-2,2-difluoroacetic acid is 205.99 g/mol.
Where can I buy 2-(4-Chlorophenyl)-2,2-difluoroacetic acid?
You can request a quote for 2-(4-Chlorophenyl)-2,2-difluoroacetic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-Chlorophenyl)-2,2-difluoroacetic acid?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-Chlorophenyl)-2,2-difluoroacetic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.