鹽酸左西替利嗪
TL;DR: 鹽酸左西替利嗪 (CAS 130018-77-8) is a chemical compound with molecular formula C21H27Cl3N2O3 and molecular weight 460.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
鹽酸左西替利嗪
2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride
Also Known As: Levocetirizine dihydrochloride, Xyzal, Xusal, Levocetirizine 2HCl, Levocetirizine HCl
| Molecular Formula | C21H27Cl3N2O3 |
|---|---|
| Molecular Weight | 460.11 g/mol |
| LogP | 3.9918 |
| Topological Polar Surface Area | 53.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 460.10873 |
| Heavy Atoms | 29 |
| Complexity | 723.711 |
Chemical Identifiers
| CAS Number | 130018-77-8 |
|---|---|
| SMILES | C1CN(CCN1CCOCC(=O)O)[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl |
Product Overview
鹽酸左西替利嗪 (CAS 130018-77-8), with molecular formula C21H27Cl3N2O3 and molecular weight 460.11 g/mol. IUPAC: 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride.
Chemical Property Profile of 鹽酸左西替利嗪
Property Insights of 鹽酸左西替利嗪
The XLogP value of 3.9918 indicates that 鹽酸左西替利嗪 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.01 Ų, 鹽酸左西替利嗪 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 鹽酸左西替利嗪 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 鹽酸左西替利嗪?
The CAS number of 鹽酸左西替利嗪 is 130018-77-8.
What is the molecular formula of 鹽酸左西替利嗪?
The molecular formula of 鹽酸左西替利嗪 is C21H27Cl3N2O3.
What is the molecular weight of 鹽酸左西替利嗪?
The molecular weight of 鹽酸左西替利嗪 is 460.11 g/mol.
Where can I buy 鹽酸左西替利嗪?
You can request a quote for 鹽酸左西替利嗪 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 鹽酸左西替利嗪?
Yes, KEHONG BIO provides custom synthesis services for 鹽酸左西替利嗪 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.