原阿片碱
TL;DR: 原阿片碱 (CAS 130-86-9) is a chemical compound with molecular formula C20H19NO5 and molecular weight 353.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
原阿片碱
15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one
Also Known As: protopine, Corydinine, Biflorine, Macleyine, Fumarine
| Molecular Formula | C20H19NO5 |
|---|---|
| Molecular Weight | 353.13 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 57.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 0 |
| Exact Mass | 353.1263 |
| Heavy Atoms | 26 |
| Complexity | 542.0 |
| Melting Point | 208 °C |
| Density | 1.399 (calc) |
| Solubility | Practically insoluble in water |
Chemical Identifiers
| CAS Number | 130-86-9 |
|---|---|
| SMILES | CN1CCC2=CC3=C(C=C2C(=O)CC4=C(C1)C5=C(C=C4)OCO5)OCO3 |
| InChIKey | GPTFURBXHJWNHR-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
原阿片碱 (CAS 130-86-9), with molecular formula C20H19NO5 and molecular weight 353.13 g/mol. IUPAC: 15-methyl-7,9,19,21-tetraoxa-15-azapentacyclo[15.7.0.04,12.06,10.018,22]tetracosa-1(17),4,6(10),11,18(22),23-hexaen-3-one.
Chemical Property Profile of 原阿片碱
Property Insights of 原阿片碱
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 原阿片碱. With a topological polar surface area (TPSA) of 57.2 Ų, 原阿片碱 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 原阿片碱 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 原阿片碱?
The CAS number of 原阿片碱 is 130-86-9.
What is the molecular formula of 原阿片碱?
The molecular formula of 原阿片碱 is C20H19NO5.
What is the molecular weight of 原阿片碱?
The molecular weight of 原阿片碱 is 353.13 g/mol.
Where can I buy 原阿片碱?
You can request a quote for 原阿片碱 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 原阿片碱?
Yes, KEHONG BIO provides custom synthesis services for 原阿片碱 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.