8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer
TL;DR: 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer (CAS 129735-00-8) is a chemical compound with molecular formula C10H11BrN5O5PS and molecular weight 422.94 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(6-amino-8-bromopurin-9-yl)-2-hydroxy-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
Also Known As: 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer, 6-(6-amino-8-bromopurin-9-yl)-2-hydroxy-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol, Adenosine, 8-bromo-, cyclic 3',5'-[hydrogen [P(R)]-phosphorothioate], 8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt
| Molecular Formula | C10H11BrN5O5PS |
|---|---|
| Molecular Weight | 422.94 g/mol |
| LogP | 0.0615 |
| Topological Polar Surface Area | 137.77 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 1 |
| Exact Mass | 422.9402 |
| Heavy Atoms | 23 |
| Complexity | 835.3197 |
Chemical Identifiers
| CAS Number | 129735-00-8 |
|---|---|
| SMILES | C1C2C(C(C(O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=S)(O1)O |
Product Overview
8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer (CAS 129735-00-8), with molecular formula C10H11BrN5O5PS and molecular weight 422.94 g/mol. IUPAC: 6-(6-amino-8-bromopurin-9-yl)-2-hydroxy-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol.
Chemical Property Profile of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer
Property Insights of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer
The XLogP value of 0.0615 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer. The TPSA of 137.77 Ų falls within the moderate polarity range, balancing permeability and solubility for 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer. Following Lipinski's Rule of Five, 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer?
The CAS number of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer is 129735-00-8.
What is the molecular formula of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer?
The molecular formula of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer is C10H11BrN5O5PS.
What is the molecular weight of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer?
The molecular weight of 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer is 422.94 g/mol.
Where can I buy 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer?
You can request a quote for 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer?
Yes, KEHONG BIO provides custom synthesis services for 8-Bromoadenosine-3',5'-cyclic monophosphorothioate, Rp-isomer and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.