奈韦拉平
TL;DR: 奈韦拉平 (CAS 129618-40-2) is a chemical compound with molecular formula C15H14N4O and molecular weight 266.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
奈韦拉平
2-cyclopropyl-7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
Also Known As: nevirapine, Viramune, Nevirapine anhydrous, Viramune XR, Nevirapine teva
| Molecular Formula | C15H14N4O |
|---|---|
| Molecular Weight | 266.12 g/mol |
| LogP | 2.0 |
| Topological Polar Surface Area | 58.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 266.11676 |
| Heavy Atoms | 20 |
| Complexity | 397.0 |
| Melting Point | 196.06 |
| Solubility | 0.7046 |
| Vapor Pressure | 3.4X10-9 mm Hg @ 25 °C /Estimated/ |
Chemical Identifiers
| CAS Number | 129618-40-2 |
|---|---|
| SMILES | CC1=C2C(=NC=C1)N(C3=C(C=CC=N3)C(=O)N2)C4CC4 |
| InChIKey | NQDJXKOVJZTUJA-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
奈韦拉平 (CAS 129618-40-2), with molecular formula C15H14N4O and molecular weight 266.12 g/mol. IUPAC: 2-cyclopropyl-7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one.
Chemical Property Profile of 奈韦拉平
Property Insights of 奈韦拉平
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 奈韦拉平. With a topological polar surface area (TPSA) of 58.1 Ų, 奈韦拉平 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 奈韋拉平 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 奈韋拉平?
The CAS number of 奈韋拉平 is 129618-40-2.
What is the molecular formula of 奈韋拉平?
The molecular formula of 奈韋拉平 is C15H14N4O.
What is the molecular weight of 奈韋拉平?
The molecular weight of 奈韋拉平 is 266.12 g/mol.
Where can I buy 奈韋拉平?
You can request a quote for 奈韋拉平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 奈韋拉平?
Yes, KEHONG BIO provides custom synthesis services for 奈韋拉平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.