21-Fluoropromegestone
TL;DR: 21-Fluoropromegestone (CAS 128855-74-3) is a chemical compound with molecular formula C22H29FO2 and molecular weight 344.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,13S,14S,17S)-17-[(2R)-2-fluoropropanoyl]-13,17-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Also Known As: 21-Fluoropromegestone, 21(R)-Fluoro-R5020, 21(S)-Fluoro-R5020, 21-F-R 5020, (17beta(S))-17-(2-Fluoro-1-oxopropyl)-17-methylestra-4,9-dien-3-one
| Molecular Formula | C22H29FO2 |
|---|---|
| Molecular Weight | 344.22 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 34.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 344.21515 |
| Heavy Atoms | 25 |
| Complexity | 703.0 |
Chemical Identifiers
| CAS Number | 128855-74-3 |
|---|---|
| SMILES | C[C@H](C(=O)[C@]1(CC[C@@H]2[C@@]1(CCC3=C4CCC(=O)C=C4CC[C@@H]23)C)C)F |
| InChIKey | AQJLFHHHAYTPCE-PWGGLJECSA-N |
Product Overview
21-Fluoropromegestone (CAS 128855-74-3), with molecular formula C22H29FO2 and molecular weight 344.22 g/mol. IUPAC: (8S,13S,14S,17S)-17-[(2R)-2-fluoropropanoyl]-13,17-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 21-Fluoropromegestone
Property Insights of 21-Fluoropromegestone
The XLogP value of 3.6 indicates that 21-Fluoropromegestone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.1 Ų, 21-Fluoropromegestone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 21-Fluoropromegestone has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 21-Fluoropromegestone?
The CAS number of 21-Fluoropromegestone is 128855-74-3.
What is the molecular formula of 21-Fluoropromegestone?
The molecular formula of 21-Fluoropromegestone is C22H29FO2.
What is the molecular weight of 21-Fluoropromegestone?
The molecular weight of 21-Fluoropromegestone is 344.22 g/mol.
Where can I buy 21-Fluoropromegestone?
You can request a quote for 21-Fluoropromegestone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 21-Fluoropromegestone?
Yes, KEHONG BIO provides custom synthesis services for 21-Fluoropromegestone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.