N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide
TL;DR: N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide (CAS 1285536-46-0) is a chemical compound with molecular formula C19H20N4OS and molecular weight 352.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(5-methylthiophen-2-yl)-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-1H-pyrazole-3-carboxamide
Also Known As: N'-(4-Isopropylbenzylidene)-3-(5-methylthiophen-2-yl)-1H-pyrazole-5-carbohydrazide, N'-(4-ISOPROPYLBENZYLIDENE)-3-(5-METHYL-2-THIENYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE, 3-(5-methylthiophen-2-yl)-N'-{(E)-[4-(propan-2-yl)phenyl]methylidene}-1H-pyrazole-5-carbohydrazide, (E)-N'-(4-isopropylbenzylidene)-3-(5-methylthiophen-2-yl)-1H-pyrazole-5-carbohydrazide, 5-(5-methylthiophen-2-yl)-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-1H-pyrazole-3-carboxamide
| Molecular Formula | C19H20N4OS |
|---|---|
| Molecular Weight | 352.14 g/mol |
| LogP | 4.33392 |
| Topological Polar Surface Area | 70.14 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 352.13577 |
| Heavy Atoms | 25 |
| Complexity | 890.3022 |
Chemical Identifiers
| CAS Number | 1285536-46-0 |
|---|---|
| SMILES | CC1=CC=C(S1)C2=CC(=NN2)C(=O)N/N=C/C3=CC=C(C=C3)C(C)C |
Product Overview
N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide (CAS 1285536-46-0), with molecular formula C19H20N4OS and molecular weight 352.14 g/mol. IUPAC: 5-(5-methylthiophen-2-yl)-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]-1H-pyrazole-3-carboxamide.
Chemical Property Profile of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide
Property Insights of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide
The XLogP value of 4.33392 indicates that N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.14 Ų falls within the moderate polarity range, balancing permeability and solubility for N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide?
The CAS number of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide is 1285536-46-0.
What is the molecular formula of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide?
The molecular formula of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide is C19H20N4OS.
What is the molecular weight of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide?
The molecular weight of N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide is 352.14 g/mol.
Where can I buy N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide?
You can request a quote for N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for N'-(4-Isopropylbenzylidene)-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.