Z-2-Nal-chloromethylketone
TL;DR: Z-2-Nal-chloromethylketone (CAS 128019-71-6) is a chemical compound with molecular formula C22H20ClNO3 and molecular weight 381.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
benzyl N-[(2S)-4-chloro-1-naphthalen-2-yl-3-oxobutan-2-yl]carbamate
Also Known As: Z-2-Nal-chloromethylketone, Z-L-Ala(2-naphthyl)-CMK, acs.jmedchem.1c00409_ST.148, 4-N-Boc-Piperazine-2-carboxylicacid, z-3-(2-Naphthyl)-L-alanine chloromethylketone
| Molecular Formula | C22H20ClNO3 |
|---|---|
| Molecular Weight | 381.11 g/mol |
| LogP | 4.4852 |
| Topological Polar Surface Area | 55.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 381.11316 |
| Heavy Atoms | 27 |
| Complexity | 927.0039 |
Chemical Identifiers
| CAS Number | 128019-71-6 |
|---|---|
| SMILES | C1=CC=C(C=C1)COC(=O)N[C@@H](CC2=CC3=CC=CC=C3C=C2)C(=O)CCl |
Product Overview
Z-2-Nal-chloromethylketone (CAS 128019-71-6), with molecular formula C22H20ClNO3 and molecular weight 381.11 g/mol. IUPAC: benzyl N-[(2S)-4-chloro-1-naphthalen-2-yl-3-oxobutan-2-yl]carbamate.
Chemical Property Profile of Z-2-Nal-chloromethylketone
Property Insights of Z-2-Nal-chloromethylketone
The XLogP value of 4.4852 indicates that Z-2-Nal-chloromethylketone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, Z-2-Nal-chloromethylketone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Z-2-Nal-chloromethylketone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Z-2-Nal-chloromethylketone?
The CAS number of Z-2-Nal-chloromethylketone is 128019-71-6.
What is the molecular formula of Z-2-Nal-chloromethylketone?
The molecular formula of Z-2-Nal-chloromethylketone is C22H20ClNO3.
What is the molecular weight of Z-2-Nal-chloromethylketone?
The molecular weight of Z-2-Nal-chloromethylketone is 381.11 g/mol.
Where can I buy Z-2-Nal-chloromethylketone?
You can request a quote for Z-2-Nal-chloromethylketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Z-2-Nal-chloromethylketone?
Yes, KEHONG BIO provides custom synthesis services for Z-2-Nal-chloromethylketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.