PD 131628 structure

PD 131628

TL;DR: PD 131628 (CAS 127967-03-7) is a chemical compound with molecular formula C16H17FN4O3 and molecular weight 332.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-[(3S)-3-aminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Also Known As: PD 131628, CI-990 (Hydrochloride), KST-1B0147, CI 990, 7-[(3S)-3-aminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

CAS: 127967-03-7
Molecular Formula C16H17FN4O3
Molecular Weight 332.13 g/mol
LogP -0.1
Topological Polar Surface Area 99.8 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 8
Rotatable Bonds 3
Exact Mass 332.12848
Heavy Atoms 24
Complexity 594.0

Chemical Identifiers

CAS Number 127967-03-7
SMILES C1CN(C[C@H]1N)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F
InChIKey MUKSDTOOLRNSIO-QMMMGPOBSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (4 patents) Pharmaceutical Intermediates (4 patents)

Product Overview

PD 131628 (CAS 127967-03-7), with molecular formula C16H17FN4O3 and molecular weight 332.13 g/mol. IUPAC: 7-[(3S)-3-aminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of PD 131628

XLogP
-0.1
TPSA (Topological Polar Surface Area)
99.8
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
8
Rotatable Bonds
3
Heavy Atoms
24
Complexity
594.0
Exact Mass
332.12848
Monoisotopic Mass
332.12848
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of PD 131628

The XLogP value of -0.1 indicates that PD 131628 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.8 Ų falls within the moderate polarity range, balancing permeability and solubility for PD 131628. Following Lipinski's Rule of Five, PD 131628 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of PD 131628?

The CAS number of PD 131628 is 127967-03-7.

What is the molecular formula of PD 131628?

The molecular formula of PD 131628 is C16H17FN4O3.

What is the molecular weight of PD 131628?

The molecular weight of PD 131628 is 332.13 g/mol.

Where can I buy PD 131628?

You can request a quote for PD 131628 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for PD 131628?

Yes, KEHONG BIO provides custom synthesis services for PD 131628 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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