16alpha-Fluoro-5alpha-androstan-17-one structure

16alpha-Fluoro-5alpha-androstan-17-one

TL;DR: 16alpha-Fluoro-5alpha-androstan-17-one (CAS 126986-24-1) is a chemical compound with molecular formula C19H29FO and molecular weight 292.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(5R,8R,9S,10S,13S,14S,16R)-16-fluoro-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

Also Known As: Compound 8356, 16-Fluoroandrostan-17-one, 16alpha-fluoro-5alpha-androstan-17-one, KST-1A0972, 16-a-fluoro-5-a-androstan-17-one

CAS: 126986-24-1
Molecular Formula C19H29FO
Molecular Weight 292.22 g/mol
LogP 6.1
Topological Polar Surface Area 17.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 292.22025
Heavy Atoms 21
Complexity 460.0

Chemical Identifiers

CAS Number 126986-24-1
SMILES C[C@]12CCCC[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3C[C@H](C4=O)F)C
InChIKey KYYGZDIWMMQTCH-ZLOBMTTQSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (16 patents) Pharmaceutical Intermediates (65 patents)

Product Overview

16alpha-Fluoro-5alpha-androstan-17-one (CAS 126986-24-1), with molecular formula C19H29FO and molecular weight 292.22 g/mol. IUPAC: (5R,8R,9S,10S,13S,14S,16R)-16-fluoro-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 16alpha-Fluoro-5alpha-androstan-17-one

XLogP
6.1
TPSA (Topological Polar Surface Area)
17.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
21
Complexity
460.0
Exact Mass
292.22025
Monoisotopic Mass
292.22025
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 16alpha-Fluoro-5alpha-androstan-17-one

The XLogP value of 6.1 indicates that 16alpha-Fluoro-5alpha-androstan-17-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.1 Ų, 16alpha-Fluoro-5alpha-androstan-17-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 16alpha-Fluoro-5alpha-androstan-17-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 16alpha-Fluoro-5alpha-androstan-17-one?

The CAS number of 16alpha-Fluoro-5alpha-androstan-17-one is 126986-24-1.

What is the molecular formula of 16alpha-Fluoro-5alpha-androstan-17-one?

The molecular formula of 16alpha-Fluoro-5alpha-androstan-17-one is C19H29FO.

What is the molecular weight of 16alpha-Fluoro-5alpha-androstan-17-one?

The molecular weight of 16alpha-Fluoro-5alpha-androstan-17-one is 292.22 g/mol.

Where can I buy 16alpha-Fluoro-5alpha-androstan-17-one?

You can request a quote for 16alpha-Fluoro-5alpha-androstan-17-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 16alpha-Fluoro-5alpha-androstan-17-one?

Yes, KEHONG BIO provides custom synthesis services for 16alpha-Fluoro-5alpha-androstan-17-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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